Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...
Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...
New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.
Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of ...
Biologists have used machine learning, a type of AI, to identify 'synthetic extreme' DNA sequences with specifically designed functions in gene activation. They tested 50 million DNA sequences and ...
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered how a protein long known to be an essential activator of DNA replication actually triggers this process in cells. The protein, called ...
Clinical application of targeted deep sequencing for predicting responsiveness to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in never-smoking lung adenocarcinomas (NSLA) ...
Oestrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of processes, which is why the ...
Epigenetics is often defined as the study of heritable changes that occur without a change in the actual DNA sequences. It has been shown that associated DNA proteins, called histones, are altered by ...