Yaguajay is a municipality and town in the Sancti Spíritus Province of Cuba. It is located in the northern part of the province, and borders th…Yaguajay is a municipality and town in the Sancti Spíritus Province of Cuba. It is located in the northern part of the province, and borders the Bay of Buena Vista to the north. The Caguanes National Park is located in Yaguajay.